[Home ] [Archive]   [ فارسی ]  
:: Volume 5, Issue 3 (Vol.5, No.3, autumn 2017) ::
J Neyshabur Univ Med Sci 2017, 5(3): 1-8 Back to browse issues page
A Review on Amyloid Beta Peptides and Tau Proteins Involved in the Alzheimer’s Disease
Masoud Soheili *1, Leyla Ara, Seyyed Mojtaba Bani Taba Bidgoli, Mahmoud Salami
1- , soheili_masoud@yahoo.com
Abstract:   (9054 Views)
Alzheimer’s disease as a neurodegenerative disorder is known as a main cause of cognitive problems including learning and memory.  Indeed, more than half of people with senile dementia suffer from the disease. The Alzheimer’s disease is resulted from numerous factors such as biochemical disorders in protein production, uncontrolled electrical activity of neurons and changes in level of some key neurotransmitters in the brain. Oxidative stresses, increased glutamate dependent neurotoxicity, decreased release of acetyl choline and inflammation of the brain tissue are the main factors involving in the Alzheimer’s disease. However, abnormal forms of amyloid beta peptides as well as tau proteins have key role in emergence of the disease. The present study reviews the critical involvement of amyloid beta peptides and tau proteins in modification of neuronal function leading to the Alzheimer’s disease.
Keywords: Alzheimer’s disease, Amyloid beta, Tao proteins, Dementia
Full-Text [PDF 583 kb]   (1421 Downloads)    
Type of Study: Review Article | Subject: Physiology
Received: 2017/05/31 | Revised: 2018/03/6 | Accepted: 2017/12/25 | Published: 2018/03/5 | ePublished: 2018/03/5
Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Soheili M, Ara L, Bani Taba Bidgoli S M, Salami M. A Review on Amyloid Beta Peptides and Tau Proteins Involved in the Alzheimer’s Disease. J Neyshabur Univ Med Sci. 2017; 5 (3) :1-8
URL: http://journal.nums.ac.ir/article-1-320-en.html

Volume 5, Issue 3 (Vol.5, No.3, autumn 2017) Back to browse issues page
مجله علوم پزشکی نیشابور J Neyshabur Univ Med Sci

*** هرگونه کپی برداری از این سایت بدون ذکر منبع غیر قانونی و همراه با پیگیری های قضایی می باشد *** مجله دانشکده علوم پزشکی نیشابور *** Any copying of this site without citing the source is illegal And is associated with the pursuit of justice ***

Persian site map - English site map - Created in 0.21 seconds with 31 queries by YEKTAWEB 3970