[Home ] [Archive]   [ فارسی ]  
:: Volume 7, Issue 1 (Vol.7, No.1,spring 2019) ::
J Neyshabur Univ Med Sci 2019, 7(1): 112-121 Back to browse issues page
The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats
Anahita Salehi1 , Parvin Farzanegi * 2, Hajar Abbaszadeh1
1- Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran
2- Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran , parvin.farzanegi@gmail.com
Abstract:   (353 Views)
Introduction
Diabetes is the leading cause of mortality. Therefore, the purpose of this study was to investigate the effect of interval and continuous training with resveratrol on the apoptosis markers (Bax and Bcl2) of heart tissue in streptozotocin-induced diabetic rats.
Materials and Methods
In this experimental study, wistar male rats were divided into 8 groups (control-healthy (n=7), control diabetes (n=7), diabetes-saline, diabetes-supplement, diabetes-continuous training, diabetes-interval training, diabetes- continuous training- supplement, and diabetes- interval training -supplement).
The main continuous training program included 8 weeks, five sessions per week, 15-20 m / min and 60 minutes and interval training included 8 weeks, 3 sessions per week. Resveratrol at a dose of 20 mg per kg body weight was injected to the supplement groups.  The rats have been sacrificed 48 hours after the last trainingand supplements session> Then, the heart tissue is removed and used to measure the desired variables.
Results
The heart levels of BAX and Bcl2 showed a significant difference between the groups (P = 0.046). The data showed a significant difference between the control diabetes with the diabetes-supplement, diabetes-continuous training, diabetes-interval training, diabetes- continuous training- supplement, diabetes- interval training -supplement (P <0.001).
Conclusion
The results of this study showed that exercise trainings increase the Bcl2 and decrease Bax levels. This improvement was higher when resveratrol was used.
Keywords: Continuous Exercise, Interval Exercise, Diabetes, Antioxidant, resveratrol
Full-Text [PDF 1139 kb]   (38 Downloads)    
Type of Study: Orginal Article | Subject: Physiology
Received: 2018/10/9 | Revised: 2019/05/19 | Accepted: 2019/01/3 | ePublished ahead of print: 2019/02/26 | Published: 2019/01/14 | ePublished: 2019/01/14
Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

salehi A, farzanegi P, abbaszadeh H. The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats. J Neyshabur Univ Med Sci. 2019; 7 (1) :112-121
URL: http://journal.nums.ac.ir/article-1-609-en.html


Volume 7, Issue 1 (Vol.7, No.1,spring 2019) Back to browse issues page
مجله علوم پزشکی نیشابور J Neyshabur Univ Med Sci

*** هرگونه کپی برداری از این سایت بدون ذکر منبع غیر قانونی و همراه با پیگیری های قضایی می باشد *** مجله دانشکده علوم پزشکی نیشابور *** Any copying of this site without citing the source is illegal And is associated with the pursuit of justice ***

Persian site map - English site map - Created in 0.14 seconds with 31 queries by YEKTAWEB 3870