[Home ] [Archive]   [ فارسی ]  
:: ::
Back to the articles list Back to browse issues page
The Effect of Resistance Training on Protein-D Surfactant and Insulin Resistance Index in Healthy and Type 2 Diabetic Rats
Mohamm Parastesh Mr * 1, Abbas Saremi Mr2 , Abbas Salehikia Mr3
1- Arak University , mohamad.parasteah@gmail.com
2- Arak University
3- University of Sistan and Baluchestan, Zahedan, Iran.
Abstract:   (142 Views)
Introduction
Protein-D Surfactant (SPD) is a new factor associated with glucose intolerance, insulin resistance and type 2 diabetes.The aims of present study was to investigate effects of resistance training on surfactant protein-D in streptozotocin–nicotinamide induced diabetic rats.
Materials and Methods
In this experimental study، 48 adult male Wistar rats in the weight range of 200±48gr, randomly assigned in to four groups: healthy control, diabetic control, diabetic resistance training and healthy resistance training. For induction of diabetes, intraperitoneal injection of nicotinamide solution  and STZ solution was used. The training groups performed a resistance training program for 10 weeks.Data were analyzed using one-way ANOVA and Tuky  Post Hoc test at 0.05%.
Results
Resistance training caused a significant decrease in blood glucose in the resistance diabetic training group compared to the diabetic control group (P=0.024). Serum Protein-D Surfactant (SPD) serum levels in the diabetic control group significantly decreased (P=0.042) and the insulin resistance index (P=0.024) was significantly lower than healthy controls. 8 weeks of endurance training significantly increased in SPD in endurance diabetic training group compared to diabetic control group (P=0.043). Also, exercise significantly decreased insulin resistance index (P=0.034) and insulin in endurance diabetic training group compared to diabetic control group (P=0.046).
Conclusion
The results of this study seem to confirm the role of Protein-D Surfactant associated with resistance training in improving insulin resistance index in type 2 diabetic rats.
 
Keywords: Rat, Streptozotocin–nicotinamide, SPD, Insulin, Resistance training.
     
Type of Study: Orginal Article | Subject: Physiology
Received: 2018/12/31 | Revised: 2019/04/7 | Accepted: 2019/04/11 | ePublished ahead of print: 2019/05/21
Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print



Back to the articles list Back to browse issues page
مجله علوم پزشکی نیشابور J Neyshabur Univ Med Sci

*** هرگونه کپی برداری از این سایت بدون ذکر منبع غیر قانونی و همراه با پیگیری های قضایی می باشد *** مجله دانشکده علوم پزشکی نیشابور *** Any copying of this site without citing the source is illegal And is associated with the pursuit of justice ***

Persian site map - English site map - Created in 0.21 seconds with 31 queries by YEKTAWEB 3879