[Home ] [Archive]   [ فارسی ]  
:: Volume 6, Issue 4 (Vol.6, No.4,winter 2019) ::
J Neyshabur Univ Med Sci 2019, 6(4): 35-45 Back to browse issues page
Evaluation of Lnc13 relative expression comparing to healthy volunteers and correlation with clinicopathological feature
. Naghmeh Zamani Miss1 , Farzaneh Tafvizi Mrs. * 2, Mohammad Rostami Nejad Mr.3
1- Islamic Azad University
2- Islamic Azad University , farzanehtafvizi54@gmail.com
3- Shahid Beheshti University of Medical Sciences
Abstract:   (992 Views)
Celiac disease has been known to be one of the health concerns with an increasing trend worldwide. This autoimmune disease is due to a reaction to gluten resulting in destroyed intestinal villi. Recent studies have shown that Lnc13 affects the pathogenicity of the disease. However, recent studies showed that this group of genes can affect the inflammation due to the disease. We aimed to evaluate the expression of Lnc13 in Iranian celiac patients.
Materials and Methods
In this case-control study, a total of 50 celiac patients and 20 healthy controls blood samples were collected during the 1396-1395 years that referred to the Research Institute for Gastroenterology and Liver Diseases, ShahidBeheshti University of Medical Sciences, Tehran, Iran. To evaluate the relative expression of LncRNA13, the qRT-PCR method was applied.
Significantly correlation between Lnc13 gene relative expression in patients with celiac disease and control group was observed (95% CI 0.5521 to 1.250, P< 0.05) 
According to our investigation maybe an abnormal expression of Lnc13 gene in blood of celiac patients use as a biomarker for the direction Prognosis, diagnosis, and treatment of Celiac disease.
Keywords: LncRNA13, Long non Coding RNA, Celiac disease (CD)
Full-Text [PDF 945 kb]   (249 Downloads)    
Type of Study: Orginal Article | Subject: Genetics
Received: 2018/07/4 | Revised: 2019/03/3 | Accepted: 2018/12/31 | ePublished ahead of print: 2019/02/7 | Published: 2019/02/6 | ePublished: 2019/02/6
Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Zamani . N, Tafvizi F, Rostami Nejad M. Evaluation of Lnc13 relative expression comparing to healthy volunteers and correlation with clinicopathological feature. J Neyshabur Univ Med Sci. 2019; 6 (4) :35-45
URL: http://journal.nums.ac.ir/article-1-556-en.html

Volume 6, Issue 4 (Vol.6, No.4,winter 2019) Back to browse issues page
مجله علوم پزشکی نیشابور J Neyshabur Univ Med Sci

*** هرگونه کپی برداری از این سایت بدون ذکر منبع غیر قانونی و همراه با پیگیری های قضایی می باشد *** مجله دانشکده علوم پزشکی نیشابور *** Any copying of this site without citing the source is illegal And is associated with the pursuit of justice ***

Persian site map - English site map - Created in 0.22 seconds with 31 queries by YEKTAWEB 3970