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:: Volume 7, Issue 1 (Vol.7, No.1,spring 2019) ::
J Neyshabur Univ Med Sci 2019, 7(1): 144-156 Back to browse issues page
The Effect of Anabolic Steroid Boldenone, zizyphus jujube and training on testicular tissue damage in Wistar rats
Majid Abbaszadeh1 , Hassan Matinhomaee * 2, Parvin Farzanegi3
1- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
2- Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran , hasanmatinhomaee@gmail.com :
3- Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran
Abstract:   (508 Views)
Introduction
The use of anabolic-androgenic steroids by athletes has some effects on the structure and function of the organs of the body, such as the genital system. The purpose of this study was to investigate the effect of anabolic steroid Boldenone, endurance and resistance training on testicular tissue damage in Wistar rats
Materials and Methods
77 Wistar rats were randomly divided into the eleven equal groups: control, sham, Boldenone, Gallic acid + Resistance training + Boldenone, Resistance training + Boldenone, Gallic acid + Endurance training + Boldenone, zizyphus jujube + Endurance training + Boldenone, Endurance training + Boldenone, zizyphus jujube + Resistance training + Boldenone, Gallic acid + Boldenone, zizyphus jujube + Boldenone. The resistance exercise protocol consisted of three exercise sessions per week of the climbing ladder for eight weeks, and endurance training for each session 30 minutes at a speed of 12 m / min. Data analysis was performed by two way analysis of variance.
Results
The highest rate of tissue failure and degenerative changes were observed in the Boldenone group. The diameter and size of the Seminiferoustubules are equal and the base membrane is normal in the Boldenone + zizyphus jujube and Boldenone + Resistance training groups. However, the diameter of the tubes was different for each other in the Boldenone+ endurance training group.
Conclusion
Boldonone can damage testicular tissue structure and degenerative changes. It is possible that resistance training with jujube supplementation to endurance training can reduce the testicular tissue damage-induced the boldonone injection.
Keywords: Anabolic Steroid, Resistance and endurance training, Testicular tissue, Rat
Full-Text [PDF 1418 kb]   (362 Downloads)    
Type of Study: Orginal Article | Subject: Physiology
Received: 2018/12/8 | Revised: 2019/04/29 | Accepted: 2019/01/20 | ePublished ahead of print: 2019/04/27 | Published: 2019/04/29 | ePublished: 2019/04/29
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abbaszadeh M, matinhomaee H, farzanegi P. The Effect of Anabolic Steroid Boldenone, zizyphus jujube and training on testicular tissue damage in Wistar rats. J Neyshabur Univ Med Sci. 2019; 7 (1) :144-156
URL: http://journal.nums.ac.ir/article-1-629-en.html


Volume 7, Issue 1 (Vol.7, No.1,spring 2019) Back to browse issues page
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