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Study of Antibacterial Effect of Salvia officinalis Essence and Comparison with Chlorhexidine on some of Bacterial agents of the Oral Cavity
Hojjat Eghbal Doctor1 , Arezou Mohammadi Doctor1 , Nima Mohammad Nejad Khiavi Mr 2, Neda Jahani Doctor3
1- university of tabriz
2- Research & Development, Green Drug Reserchers , nimanejad7@yahoo.com
3- Research & Development, Green Drug Reserchers
Abstract:   (210 Views)
Introduction: Salvia officinalis is an herbaceous plant which is belong to the family of Lamiaceae (Labiatae). Salvia officinalis is one of the most important herbal plants used as a disinfectant in traditional and modern medicine. The aim of this research was to study of antibacterial Effect of Salvia officinalis essence and comparison with chlorhexidine on some of common oral infection Bbacteria.
Materials and Method: In this research, Salvia officinalis was collected from the Anzan Meshgin-Shahr area in the northwest of Iran. The essential oil was extracted by Clevengerchr('39')s apparatus, GC and GC/MS devices were used for analysis of essential oil compounds and accurate measurements of the compounds. Then, the effect of the essential oil of the Salvia officinalis and  control on the common bacteria of the oral infection evaluated in two ways: Disc deffusion And minimum inhibitory concentration (MIC).
Results: According to the results, the essential oil of the herb has a significant inhibitory effect on the types of gram negative and positive bacteria. Also, comparing the diameter of the non-growth of the plant with chlorhexin, it was found that the essence of the herb medicine showed relatively similar results to that of the chlorhexin.
Conclusion: According to the findings, essential oil of the herb has a good anti-microbial effect against the common bacteria of oral infections. As a result, the essential oil of this plant with different concentrations, after completing studies, can be an appropriate alternative for chemical drugs and chemical mouthwashes in the treatment of oral bacterial infections.

Keywords: Salvia Officinalis, Essential Oil, Oral Bacteria, Antibacterial Agents, Chlorhexidine.
Type of Study: Orginal Article | Subject: Pharmacy
Received: 2020/01/14 | Revised: 2020/10/20 | Accepted: 2020/11/6 | ePublished ahead of print: 2021/01/23
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